HomeAboutContact usSite mapSearch
Fiche des professeurs
Professors

Alan Anderson

Professor

Contact informations :
Office : VCH 3036-A
Phone : (418) 691-5281
Fax : (418) 691-5439
E-mail : Alan.Anderson@bio.ulaval.ca

University and professionnal qualifications :

Director of the undergraduate program

Research fields :

Regulation of the expression of rat genes for cytochrome P450 2B proteins.

Research programs :

The regulation of the expression of the phenobarbital-inducible CYP2B2 gene is being studied in primary cultures of hepatocytes from adult rats. This system has permitted us to identify a phenobarbital response unit (PBRU) in the 5'-flanking region of the CYP2B2 gene.

Publications :
  • Beaudet, M-J., M. Desrochers, A. Lachaud & A. Anderson (2005). "The CYP2B2 phenobarbital response unit contains binding sites for hepatocyte nuclear factor 4, PBX-Prep1, the thyroid hormone receptor ß, and the liver X receptor", Biochem. J. 388(Pt 2): 407-18,  
      
  • Roberge, C., M-J. Beaudet and A. Anderson (2004). "GABAA/central benzodiazepine receptor and peripheral benzodiazepine receptor ligands as inducers of phenobarbital-inducible CYP2B and CYP3A", Biochem. Pharamcol. 68, 1383-1389,  
      
  • Paquet,Y. E. Trottier, M-J. Beaudet & A. Anderson (2000). "Mutational analysis of the CYP2B2 phenobarbital response unit and inhibitory effect of the constitutive androstane receptor on phenobarbital responsiveness", J. Biol. Chem. 275, 38427-38436,  
      
  • Courtemanche,C. & A. Anderson (1999). "Multiple mutations in a shuttle vector modified by ultraviolet irradiation, (±)7,8-dihydroxy-9,10- epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene, and aflatoxin B1 have different properties than single mutations and may be generated during translesion synthesis", Mutat. Res. 430, 23-36,  
      
  • Courtemanche, C. & A. Anderson (1999). "The p53 tumor suppressor protein reduces point mutation frequency of a shuttle vector modified by the chemical mutagens (±)7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo [a]pyrene, aflatoxin B1 and meta-chloroperoxybenzoic acid", Oncogene, 18, 4672-4680,  
      
All publications

Autumn courses :
  • BIO-7016 :  Génétique moléculaire (aux deux ans; automne 2006)

  • BIO-7001 :  Progrès récents en biologie moléculaire

  • BIO-7002 :  Séminaire de biologie cellulaire et moléculaire
Winter courses :


Back to teachers list
Département de biologie,  Pavillon Alexandre-Vachon, 1045, av. de la Médecine, Local 3058
Québec (Québec) G1V 0A6 Canada
Téléphone : 418 656-3180  Courriel : info@bio.ulaval.ca
Ce site utilise TYPO3
Réalisation: Équipe Tactic